Found insideThis book provides a thorough review of the mechanisms by which oxidative stress and redox signalling mediate Parkinson’s Disease. This new edition builds upon the success of the first edition, with comprehensive scientific and clinical updates of all chapters. Found insideThis book summarizes the current state of movement disorder management and the role of surgical therapies as an alternative to medication. Found insideKnowledge at-a-glance on all aspects of Parkinson's and related syndromes The only resource of its kind, this is a concise yet comprehensive overview of Parkinson's disease and related syndromes written for PAs, medical students, case ... The book is essential reading for clinicians working in neurology, psychiatry and geriatric medicine. This book is recommended for anyone interested in how and why balance control is affected by PD. Provides the first comprehensive review of research to date on balance dysfunctions in Parkinson's disease Discusses how to translate current ... Reflecting these changes, this second edition features new chapters devoted to genetic aspects of PD, non-motor features of the disease, and aspects of the pathophysiology, pathogenesis, and treatment of PD. Found insideIt represents the functional changes that occur because of injury or disease. This volume provides state-of-the-art up-to-date literature reviews on pathophysiological processes in a number of disease states. This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. An authoritative collection of recent breakthroughs in Parkinson's Disease (PD) research, Parkinson’s Disease: Genetics and Pathogenesis spans key findings on the mechanisms of neurodegeneration and the role of specific genes that may ... "Mucuna versus Parkinson: Natural Levodopa Treatment" is so far the most complete and up-to-date monograph on the subject, it describes the theoretical and practical approaches to the use of this plant as a treatment option for Parkinson's ... This book contains some path-breaking studies in Parkinson's disease. It explores the fundamental as well as the modern understanding of the symptoms, pathophysiology and treatment of Parkinson's disease. This is clearly true for the various motor system abnormalities, which are not fully corrected by dopamine replacement therapy strategies, but also for the nonmotor system abnormalities that are the subject of this volume. The second edition of Parkinson's Disease: Diagnosis and Clinical Management provides a state-of-the-art review of where we've been, where we are now, and where we are going in treating this disease. Part of Springer’s “The Receptors,” series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary ... Found insideThe book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. Parkinson's disease (PD) results primarily from the death of dopaminergic neurons in the substantia nigra. Current PD medications treat symptoms; none halt or retard dopaminergic neuron degeneration. At present, there are several neuroprotective therapies in the experimental pipeline, but these are for the patients of tomorrow. This book focuses on two therapies that are readily available for the patients of today. In this book, the ecological and biological agents which become the cause of Parkinson's disease have bee This book presents the latest research on the pathways and mechanisms that have been discovered to play a role in Parkinson's pathology. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for ... Effective and modern treatment strategies for those newly diagnosed with Parkinson's Whether it's you or a family member, receiving a diagnosis of Parkinson's disease can generate emotions of anger, frustration, sadness, and confusion--but ... Efforts in this direction are worthy as they will reduce the burden of PD among elderly, who are already burdened with age related systemic degenerative processes. This book is a humble effort in that progressive direction. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. Indeed, the book covers virtually every topic related to Parkinson's, from sexual impotence and skin rashes, to the role of nutrition, exercise, and physical therapy. This textbook aims to tell the full story of non-motor and non-dopaminergic features of Parkinson's Disease. This first volume starts with an overview on current perspectives in genetic research and on the molecular mechanisms of neurodegeneration. Found insideParkinsons disease is a disabling neurological condition with both motor and non-motor symptoms for which no cure is available at this stage. This book is unique in covering the most important topics related to Parkinsons disease. Found inside – Page iiThis book offers a comprehensive approach to the wide range of movement disorders, an important specialty in the field of neurology, guiding readers from the phenomenology to diagnosis and management. Found insideAs the most exciting molecule,dopamine directly impacts day-to-day life. Anyone who has an eye for health and disease-related concepts will find this book a good read. Hyperkinetic Movement Disorders is a state-of-the-art resource devoted to disorders characterized by excessive movement. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more ... Found insideThis practical handbook reflects the importance of addressing non-motor symptoms, the need for multidisciplinary care and the use of tools that empower patients. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. Provides a broad overview of current rehabilitation approaches, emphasizing the need for interdisciplinary management and focussing on deliverable outcomes. This book about Parkinson's disease provides a detailed account of etiology and pathophysiology of Parkinson's disease, a complicated neurological condition. Found insideThis book provides up-to-date reviews on current animal models of both HD and PD. These animal models are essential to investigate links between the pathobiology and the behavioral abnormalities associated with these disorders. Found insideAdditionally, the presence of a number of circuits within the basal ganglia related to non-motor functions has been acknowledged. Currently, the basal ganglia are thought to participate in cognitive, limbic and learning functions. 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